aptaselect
AptaSelect identifies high-frequency aptamer candidate sequences from paired-end FASTQ files produced by SELEX experiments. The pipeline joins paired-end reads, applies three sequential pattern-based filtering stages (Selection, 1st Sort, 2nd Sort), and aggregates and ranks sequences by frequency at each stage. An optional motif-analysis step extracts the variable core between two experiment-specific flanking motifs from the top-ranked sequences, writes those cores to FASTA, and runs MEME to discover the shared motif.
Based on: aptaselect v1.0.1 by khyeonm
VERSION 1.0.2
AUTHOR khyeonm
INPUT Read 1 FASTQRead 2 FASTQ
OUTPUT Frequency-ranked sequence lists (TSV)Pipeline summary statisticsVariable cores extracted between the two flanking motifs (FASTA)MEME motif-discovery results (meme_out)
FILES
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